DSpace About DSpace Software
 

DSpace Biblioteca Universidad de Talca (v1.5.2) >
Dirección de Investigación >
Artículos en publicaciones ISI - Universidad de Talca >

Please use this identifier to cite or link to this item: http://dspace.utalca.cl/handle/1950/10180

Title: Statistics of extreme events in risk management: The impact of the subprime and global financial crisis on the German stock market
Authors: Herrera, R.
Schipp, B.
Keywords: Subprime crisis
German stock market
Extreme value theory
Value at Risk
Issue Date: Jul-2014
Publisher: ELSEVIER SCIENCE INC
Citation: NORTH AMERICAN JOURNAL OF ECONOMICS AND FINANCE 29 : 218-238
Abstract: Chronic inflammation constitutes an important link between obesity and its pathophysiological sequelae. In contrast to the belief that inflammatory signals exert a fundamentally negative impact on metabolism, we show that proinflammatory signaling in the adipocyte is in fact required for proper adipose tissue remodeling and expansion. Three mouse models with an adipose tissue-specific reduction in proinflammatory potential were generated that display a reduced capacity for adipogenesis in vivo, while the differentiation potential is unaltered in vitro. Upon high-fat-diet exposure, the expansion of visceral adipose tissue is prominently affected. This is associated with decreased intestinal barrier function, increased hepatic steatosis, and metabolic dysfunction. An impaired local proinflammatory response in the adipocyte leads to increased ectopic lipid accumulation, glucose intolerance, and systemic inflammation. Adipose tissue inflammation is therefore an adaptive response that enables safe storage of excess nutrients and contributes to a visceral depot barrier that effectively filters gut-derived endotoxin.
Description: Univ Talca, Fac Econ & Negocios, Talca, Chile. Herrera, R (Herrera, Rodrigo)
URI: http://dspace.utalca.cl/handle/1950/10180
ISSN: 1879-0860
Appears in Collections:Artículos en publicaciones ISI - Universidad de Talca

Files in This Item:

File Description SizeFormat
TEXTO_COMPLETO.htmlDESCARGAR3.08 kBHTMLView/Open

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

 

Valid XHTML 1.0! DSpace Software Copyright © 2002-2009  The DSpace Foundation - Feedback