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Title: | Prevalence of heparin-induced antibodies in patients with chronic renal failure undergoing hemodialysis |
Authors: | Palomo, I. Pereira, J. Alarcon, M. Diaz, G. Hidalgo, P. Pizarro, I. Jara, E. Rojas, P. Quiroga, G. Moore-Carrasco, R. |
Keywords: | heparin-induced antibodies; Fc gamma RIIa; hemodialysis |
Issue Date: | 2005 |
Publisher: | Wiley - Liss, Inc |
Citation: | Journal of Clinical Laboratory Analysis 19 (5): 189-195 |
Abstract: | Heparin-induced thrombocytopenia (HIT) type II is a serious complication of heparin therapy. It presents initially as thrombocytopenia, and is associated with thrombosis in 20-50% of the cases. HIT is related to the presence of heparin-induced antibodies (HIA), which show specificity for the PF4-heparin (PF4-H) complex. The Fc gamma RIIa receptor has been suggested to participate in the pathogenic mechanism of HIA |
Description: | Palomo, I.; Alarcon, M.L.; Jara, E.; Rojas, P.; Quiroga, G. and Moore-Carrasco, R. Department of Clinical Biochemistry and Immunohematology, Faculty of Health Sciences, Universidad de Talca, Casilla N° 747, Talca, |
URI: | http://dspace.utalca.cl/handle/1950/3346 |
ISSN: | 0887-8013 |
Appears in Collections: | Artículos en publicaciones ISI - Universidad de Talca
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