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| Title: | DNA binding alkaloids from Lobelia bridgesii hook et arn and Lobelia tupa L |
| Authors: | Marambio, O.
Monsalve, E.
Schmeda-Hirschmann, G. |
| Keywords: | Lobelia bridgesii, L. tupa, Lobelioideae, DNA binding, alkaloids, norlobelanidine, norlelobanidine.
Lobelia bridgesii, L. tupa, Lobelioideae, unión al ADN, alcaloides, norlobelanidina, norlelobanidina |
| Issue Date: | 1999 |
| Publisher: | Sociedad Chilena de Quimica |
| Citation: | Boletin de la Sociedad Chilena de Quimica 44(3): 385-389 |
| Abstract: | The methanolic extract of the aerial parts of Lobelia bridgesii and L. tupa (Lobeliaceae) showed activity in the DNA binding assay. Bioassay-guided isolation led to the alkaloids norlobelanidine and norlelobanidine as the main bioactive constituents of othe plant. At 0.50 mg/mL, the percentual DNA binding of both compounds were 79% and 71%, respectively |
| Description: | Schmeda-Hirschmann, G. Laboratorio de Química de Productos Naturales, Instituto de Química de Recursos Naturales, Universidad de Talca, Casilla 747, Talca, Chile. |
| URI: | http://dspace.utalca.cl/handle/1950/4146 |
| ISSN: | 0366-1644 |
| Appears in Collections: | Artículos en publicaciones ISI - Universidad de Talca
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