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Please use this identifier to cite or link to this item: http://dspace.utalca.cl/handle/1950/4318

Title: Naphthoquinone derivatives and lignans from the Paraguayan crude drug
Authors: Schmeda-Hirschmann, G.
Papastergiou, F.
Keywords: Tabebuia heptaphylla; Bignoniaceae; naphthoquinones
Issue Date: 2003
Publisher: Verlag Z Naturforsch
Citation: Zeitschrift Fur Naturforschung C-A Journal of Biosciences 58 (7-8): 495-501
Abstract: The Paraguayan crude drug “tayı¨ pyta´” is used to treat cancer, wounds and inflammation. It consist of the bark and trunkwood of Tabebuia heptaphylla (Bignoniaceae). A phytochemical study of the crude drug gave, in addition to previously described naphthoquinones and the known lignans cycloolivil and secoisolariciresinol, three new lapachenol (lapachonone)-, two naphthofuran-, a chromone and a naphthalene derivative. The structures were elucidated by means of high field NMR spectroscopy. The biological activity of the main compound lapachol and the related α-lapachone as well as the lignans cycloolivil and secoisolariciresinol can explain, at least in part, the effect atributed to the crude drug in Paraguayan folk medicine.
Description: Schmeda-Hirschmann,G. Laboratorio de Quımica de Productos Naturales,Instituto de Quımica de Recursos Naturales, Universidad de Talca, Casilla 747, Talca, Chile.
URI: http://dspace.utalca.cl/handle/1950/4318
ISSN: 0939-5075
Appears in Collections:Artículos en publicaciones ISI - Universidad de Talca

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