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Please use this identifier to cite or link to this item: http://dspace.utalca.cl/handle/1950/4619

Title: Hypotensive and diuretic effect of Equisetum bogotense and Fuchsia magellanica and micropropagation of E. bogotense
Authors: Rodriguez, J.
Pacheco, P.
Razmilic, I.
Loyola, J.I.
Schmeda-Hirschmann, G.
Theoduloz, C.
Keywords: Equisetum bogotense; Fuchsia magellanica; hypotensive effect; diuretic effect; micropropagation
Issue Date: 1994
Publisher: John Wiley & Sons Ltd.
Citation: Phytotherapy Research 8 (3): 157-160
Abstract: Equisetum bogotense (Equisetaceae) and Fuchsia magellanica (Onagraceae) were used by the Mapuche Amerindians as diuretics. Intravenous administration of hydroalcoholic extracts to rats elicited a hypotensive response of -29.0% ±4.5% and -24.2% ±0.5% respectively in the mean blood pressure of normotensive animals at a dose of 5 mg crude extract/kg body weight. The activity was found to be related with polar compounds. For Fuchsia, the active principles are related to tannins. A single oral dose of 500 mg/kg body weight Equisetum extract produced a significant increase (p < 0.05) in the urine output in rats, while in Fuchsia a reduction in diuresis was observed. The diuretic effect of the Equisetum extract was weak compared with hydrochlorothiazide at 25 mg/kg body weight. The data presented support the use of E. bogotense in Chilean traditional medicine. A micropropagation method for E. bogotense was established by culturing shoot tips in Murashige-Skoog medium with macro and micronutrients diluted 4-fold and containing 0.1 mg/L thiamine, 100 mg/L myoinositol, 1.0 mg/L NAA and 0.1 mg/L BAP.
Description: J. Rodriguez, P. Pacheco, I. Razmilic, J. I. Loyola, G. Schmeda-Hirschmann, C. Theoduloz Departamento Ciencias Biológicas, Universidad de Talca, Casilla 747, Talca, Chile.
URI: http://dspace.utalca.cl/handle/1950/4619
ISSN: 0951-418X
Appears in Collections:Artículos en publicaciones ISI - Universidad de Talca

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