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| Title: | Hypotensive effect and enzyme inhibition activity of mapuche medicinal plant extracts |
| Authors: | Schmeda-Hirschmann, G.
Loyola, J.I.
Sierra, J.
Retamal, R.
Rodriguez, J. |
| Keywords: | medicinal plants; Mapuche; hypotensive effect; xanthine oxidase; -glucuronidase; enzyme inhibition; brine shrimp toxicity; biological activities |
| Issue Date: | 1992 |
| Publisher: | John Wiley & Sons Ltd. |
| Citation: | Phytotherapy Research 6 (4): 184-188 |
| Abstract: | Thirty-five plant samples belonging to 30 Mapuche medicinal plants were assayed for xanthine oxidase and -glucuronidase inhibitory activity as well as for brine shrimp toxicity and hypotensive effect in normotensive rats. A high number of extracts displayed significant inhibition towards the enzyme -glucuronidase or elicited a hypotensive response. The biological activity of the assayed extracts shows some correlation with their use as digestives for treating hepatic troubles by the Mapuche Amerindians. From the ten plants displaying a hypotensive effect 20%, eight have some ethnobotanical indication suggesting that activity. |
| Description: | G. Schmeda-Hirschmann, J. I. Loyola, J. Sierra, R. Retamal, J. Rodriguez.
Departamento de Biologia, Universidad de Talca, Casilla 747, Talca, Chile. |
| URI: | http://dspace.utalca.cl/handle/1950/4623 |
| ISSN: | 0951-418X |
| Appears in Collections: | Artículos en publicaciones ISI - Universidad de Talca
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