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Please use this identifier to cite or link to this item: http://dspace.utalca.cl/handle/1950/8755

Title: Clinical relevance vs. statistical significance: Using neck outcomes in patients with temporomandibular disorders as an example
Authors: Armijo-Olivo, S.
Warren, S.
Fuentes, J.
Magee, D.J.
Keywords: Clinical relevance
Neck outcomes
Temporomandibular disorders
Effect size
Minimal important difference
Issue Date: Dec-2011
Publisher: CHURCHILL LIVINGSTONE
Citation: MANUAL THERAPY Volume: 16 Issue: 6 Pages: 563-572 DOI: 10.1016/j.math.2011.05.006
Abstract: Statistical significance has been used extensively to evaluate the results of research studies. Nevertheless, it offers only limited information to clinicians. The assessment of clinical relevance can facilitate the interpretation of the research results into clinical practice. The objective of this study was to explore different methods to evaluate the clinical relevance of the results using a cross-sectional study as an example comparing different neck outcomes between subjects with temporomandibular disorders and healthy controls. Subjects were compared for head and cervical posture, maximal cervical muscle strength, endurance of the cervical flexor and extensormuscles, and electromyographic activity of the cervical flexor muscles during the CranioCervical Flexion Test (CCFT). The evaluation of clinical relevance of the results was performed based on the effect size (ES), minimal important difference (MID), and clinical judgement. The results of this study show that it is possible to have statistical significance without having clinical relevance, to have both statistical significance and clinical relevance, to have clinical relevance without having statistical significance, or to have neither statistical significance nor clinical relevance. The evaluation of clinical relevance in clinical research is crucial to simplify the transfer of knowledge from research into practice. Clinical researchers should present the clinical relevance of their results. (C) 2011 Elsevier Ltd. All rights reserved.
Description: Author(s): Armijo-Olivo, S (Armijo-Olivo, Susan)1,2,3; Warren, S (Warren, Sharon)3; Fuentes, J (Fuentes, Jorge)3,4,5; Magee, DJ (Magee, David J.)3. Addresses: 1. Univ Alberta, Dept Phys Therapy, Fac Rehabil Med, Res Ctr, Edmonton, AB T6G 2G4, Canada 2. Aberhart Ctr, Fac Med & Dent, ARCHE, Edmonton, AB T6G 2J3, Canada 3. Univ Alberta, Fac Rehabil Med, Dept Phys Therapy, Edmonton, AB T6G 2G4, Canada 4. Univ Alberta, Fac Grad Studies & Res, Edmonton, AB T6G 2G4, Canada 5. Catholic Univ Maule, Dept Phys Therapy, Talca, Chile. E-mail Address: sla4@ualberta.ca; sharon.warren@ualberta.ca; jorgef@ualberta.ca; david.magee@ualberta.ca
URI: http://dspace.utalca.cl/handle/1950/8755
ISSN: 1356-689X
Appears in Collections:Artículos en publicaciones ISI - Universidad de Talca

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