Cyclotron production and parameters calculation of V-48 Nitinol stent for renal arteries in brachytherapy

Abstract

The Nitinol stent was bombarded in a cyclotron at a flux rate of 4 mu A/cm(2) to produce V-48 via Ti-48 (p, n) V-48 reaction. In this study dose distribution of V-48 radioactive stent was investigated for renal arteries. Version X-2.6 of the MCNP Monte Carlo radiation transport system code was employed to calculate dose distribution around the stent. As V-48 is a mixed gamma and beta particle emitter, two separate runs of MCNP for both beta and gamma particles were performed and the total deposited dose was acquired by adding the two mentioned values. In order to verify the simulation, the calculated results have been compared with previous published data for the source. Calculated results show high dose gradient near the stent and the maximum amount of dose deposits at the vessel wall. According to (AAPM) TG-60/149 protocol, the dosimetric parameters, including geometry function, G(rho,z), radial dose function, g (L) (rho), and anisotropy function, F(rho,z), were also determined.